ABACUS contains the following five cores:
1. Imaging and Intervention
This core includes a biplane flat panel angiography suite (suitable for heart and
stroke research), echocardiography, an ultrafast, 64-slice spiral CT scan, SPECT
nuclear imaging, an exercise physiology laboratory, mapping catheters for gene
therapy and electrophysiology (CARTO and NOGA) and a 6-bed recovery/procedure and
telemetry unit.
2. Vascular Biology-Gene Therapy-Biomarker Discovery Unit
This core will focus sophisticated basic science tools on the evaluation mechanisms
of CVD. It will facilitate identification/testing of new therapies (drug and genes)
to modulate the interaction between the blood and the vessel wall. It includes core
facilities for the following procedures: vascular function molecular imaging
applied proteomics gene therapy tissue banking cellular electrophysiology The
core contains a robotic protein chip facility, funded by Western
Diversification that will aid researchers in identifying abnormal protein
biomarkers that predict the presence and correlate with the severity and
activity of several cardiovascular diseases. By studying changes in protein
biomarkers, researchers may identify diseases prior to the appearance of
physical symptoms, potentially reducing health care costs and patient risk.
3. Trial Design/Data Analysis
ABACUS will provide the infrastructure needed to support data analysis and trial
implementation by existing research groups such as EPICORE, VIGOUR and APPROACH.
4. Data Acquisition and Transmission Facility (DAT Facility)
This 100 seat facility is accessible globally via high-speed Internet. It is a
networked viewing centre allowing conventional and virtual conferencing. The DAT
facility will allow data acquisition from scientists and research subjects. It is
equipped with a large screen viewing system and interactive desktops connected
via a wireless intranet. The faculty and trainees will be linked in a virtual
electronic community through VIVIDESKTM, a "made in Alberta" portal
or digital desktop environment. Secure software has been developed to
facilitate to acquire, move and analyze images and information electronically.
5. Outcomes
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